Description

1-(Bromomethyl)-2-Chloro-4-Nitrobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl, chloro, and nitro substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogenated nitrobenzene core.
• Organic Synthesis Building Block: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce functionalized benzyl groups.
• Dye and Pigment Intermediate: Employed in the production of specialized dyes and pigments due to its nitro-aromatic structure.
• Material Science Research: Used in the synthesis of monomers or ligands for advanced polymers and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new synthetic pathways.

Basic Information

Product Name	1-(Bromomethyl)-2-Chloro-4-Nitrobenzene
CAS No.	42533-63-1
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	2-Chloro-1-(bromomethyl)-4-nitrobenzene; 2-Chloro-α-bromo-4-nitrotoluene; 4-Nitro-2-chlorobenzyl bromide; (2-Chloro-4-nitrophenyl)methyl bromide; Benzene, 1-(bromomethyl)-2-chloro-4-nitro-; NSC 403107; α-Bromo-2-chloro-4-nitrotoluene
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-2-Chloro-4-Nitrobenzene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.