Description

(E)-Ethyl 2-Cyano-3-Ethoxyacrylate is a versatile α,β-unsaturated cyanoacrylate ester, a key building block in organic synthesis. Its value lies in its highly reactive dienophile and Michael acceptor properties, enabling the efficient construction of complex heterocyclic and polyfunctional molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to develop novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various heterocyclic compounds, including pyridines, pyrimidines, and fused ring systems with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced pesticide and herbicide intermediates, leveraging its reactivity to create novel molecular scaffolds.
• Diels-Alder Reactions: Serves as an efficient dienophile in cycloaddition reactions to form six-membered carbocyclic and heterocyclic rings.
• Michael Addition Substrate: Acts as an acceptor in conjugate addition reactions with various nucleophiles for carbon-carbon and carbon-heteroatom bond formation.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the development of specialty polymers, coatings, and functional materials.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	(E)-Ethyl 2-Cyano-3-Ethoxyacrylate
CAS No.	42466-67-1
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	Ethyl (E)-2-Cyano-3-ethoxyacrylate; 2-Cyano-3-ethoxyacrylic Acid Ethyl Ester; Ethyl α-Cyano-β-ethoxyacrylate; (E)-Ethyl 3-Ethoxy-2-cyanoacrylate; Ethyl 2-Cyano-3-ethoxypropenoate; NSC 163044; Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester, (E)-
EINECS	Contact for details

Quality Control

Our (E)-Ethyl 2-Cyano-3-Ethoxyacrylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.