Description

4'-Fluoro-3',5'-Dimethylacetophenone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the fluorine atom and methyl groups can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in advanced electronic displays and organic light-emitting diodes.
• Advanced Polymer Monomer: Employed in the development of specialty polymers with specific thermal, optical, or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination chemistry or cross-coupling reactions in academic and industrial labs.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	4'-Fluoro-3',5'-Dimethylacetophenone
CAS No.	42444-20-2
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	1-(4-Fluoro-3,5-dimethylphenyl)ethanone; 4-Fluoro-3,5-dimethylacetophenone; 3',5'-Dimethyl-4'-fluoroacetophenone; 4-Fluoro-3,5-dimethylphenyl methyl ketone; 4-Fluoro-α,α-dimethylacetophenone; 4-Fluoro-3,5-dimethylacetophenone; 4-Fluoro-3,5-dimethyl-1-acetylbenzene; 4-Fluoro-3,5-dimethylphenylethanone
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-3',5'-Dimethylacetophenone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.