Description

Cyclopropanecarboxylic Acid, 2-Ethylidene-3-Methyl-, Methyl Ester, (1Alpha,2Z,3Beta)- is a high-purity, stereochemically defined cyclopropane derivative serving as a critical chiral building block in advanced organic synthesis. Its unique strained-ring structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its cyclopropane moiety contributes to biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for developing specialized polymers and liquid crystals with unique thermal and optical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development and optimization of new asymmetric catalytic processes.
• Flavor & Fragrance Chemistry: Serves as a starting material for synthesizing complex, naturally-derived odorants and flavor compounds.
• Academic & Process R&D: A valuable reagent for methodological studies in organic chemistry, including cyclopropanation reactions and stereoselective synthesis.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Ethylidene-3-Methyl-, Methyl Ester, (1Alpha,2Z,3Beta)-
CAS No.	42418-98-4
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	Methyl (1α,2Z,3β)-2-ethylidene-3-methylcyclopropanecarboxylate; (1α,2Z,3β)-2-Ethylidene-3-methylcyclopropanecarboxylic acid methyl ester; (1R,2S,3S)-2-Ethylidene-3-methylcyclopropanecarboxylic acid methyl ester; trans-2-Ethylidene-3-methylcyclopropanecarboxylic acid methyl ester; Chrysanthemic acid ester derivative; Cyclopropane carboxylic acid, 2-ethylidene-3-methyl-, methyl ester, (1α,2Z,3β)-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Ethylidene-3-Methyl-, Methyl Ester, (1Alpha,2Z,3Beta)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and stereochemical composition are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.