Description

4-(4-Fluorophenyl)-1,3-thiazole-2-thiol is a specialized heterocyclic building block featuring a fluorinated phenyl ring and a thiol functional group. This compound is valued for its role as a versatile intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential drug candidates, especially in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiazole-thiol core.
• Material Science Precursor: Serves as a building block for functionalized polymers or ligands in catalytic systems.
• Chemical Synthesis: Employed in organic synthesis to introduce the 4-(4-fluorophenyl)thiazole moiety into target molecules.

Basic Information

Product Name	4-(4-Fluorophenyl)-1,3-thiazole-2-thiol
CAS No.	42365-73-1
Molecular Formula	C9H6FN1S2
Molecular Weight	211.28 g/mol
Synonyms	2-Mercapto-4-(4-fluorophenyl)thiazole; 4-(p-Fluorophenyl)-2-mercaptothiazole; 2-Thiol-4-(4-fluorophenyl)thiazole; 4-(4-Fluorophenyl)-2-thiazolethiol; 2-Mercapto-4-(4'-fluorophenyl)thiazole; 4-(4-Fluorophenyl)-1,3-thiazole-2-thione (tautomer); 42365-73-1
EINECS	Contact for details

Quality Control

Our production of 4-(4-Fluorophenyl)-1,3-thiazole-2-thiol adheres to strict internal quality protocols. Every batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Due to the thiol group, it may be susceptible to oxidation; prolonged storage under an inert atmosphere is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.