Description

4-Chloroindoline is a versatile halogenated indoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized core structure for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This intermediate is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce chlorine functionality into heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and bioactive molecules, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the indoline scaffold imparts specific biological activity.
• Material Science Research: Acts as a monomer or functional unit in the creation of advanced organic materials, including dyes, pigments, and electronic chemicals.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloroindoline
CAS No.	41910-04-9
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	4-Chloro-2,3-dihydro-1H-indole; 1H-Indole, 4-chloro-2,3-dihydro-; 4-Chloroindoline; Indoline, 4-chloro-; 4-Chloro-2,3-dihydroindole; 41910-04-9 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Chloroindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.