Description

3'-Chloromethylacetophenone is a versatile organic intermediate featuring a reactive chloromethyl group adjacent to an acetyl-substituted aromatic ring. This molecular architecture makes it a valuable building block for synthesizing more complex chemical structures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring phenethylamine or substituted acetophenone scaffolds.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and pesticides, where the chloromethyl group allows for further functionalization.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Employed in Friedel-Crafts alkylation, nucleophilic substitution, and reduction reactions to introduce functionalized aromatic groups into target molecules.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymers and advanced organic materials.

Basic Information

Product Name	3'-Chloromethylacetophenone
CAS No.	41908-12-7
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	1-(3-(Chloromethyl)phenyl)ethan-1-one; 3-Acetylbenzyl Chloride; m-Acetylbenzyl Chloride; 3'-Chloroacetophenone; 1-(3-Chloromethylphenyl)ethanone; 3-(Chloromethyl)acetophenone; (3-Acetylphenyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 3'-Chloromethylacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.