Description

2-Hydroxy-3,3-Diphenylpropanoic Acid is a versatile organic compound featuring a chiral center and a carboxylic acid functional group, making it a valuable intermediate in advanced synthesis. Its structure is critical for the production of fine chemicals and active pharmaceutical ingredients (APIs) where precise stereochemistry is required. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators that require specific stereoisomers for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Fine Chemical Production: Intermediate in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable standard and starting material in organic chemistry research for method development and compound library synthesis.

Basic Information

Product Name	2-Hydroxy-3,3-Diphenylpropanoic Acid
CAS No.	41858-47-3
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	2-Hydroxy-3,3-diphenylpropionic Acid; α-Hydroxydiphenylpropionic Acid; 3,3-Diphenyl-2-hydroxypropanoic Acid; 2-Hydroxy-3,3-diphenylpropanoate; Benzenepropanoic acid, α-hydroxy-β,β-diphenyl-; DL-2-Hydroxy-3,3-diphenylpropanoic acid; (±)-2-Hydroxy-3,3-diphenylpropanoic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3,3-Diphenylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the rigorous standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.