Description

1,4,7-Trioxa-10-Azacyclododecane is a versatile macrocyclic polyether compound, also known as a crown ether, valued for its selective metal ion binding properties. Its primary commercial significance lies in its ability to act as a phase-transfer catalyst and a complexing agent, facilitating reactions and separations in both research and industrial processes. This product is essential for professionals in pharmaceutical synthesis, advanced material science, and analytical chemistry who require high-purity, reliable chemical intermediates.

Application

• Phase-Transfer Catalyst (PTC): Used to accelerate reactions between reagents in immiscible phases, particularly in organic synthesis and polymer chemistry.
• Metal Ion Complexation: Employed in the selective extraction, separation, and purification of specific alkali and alkaline earth metal cations.
• Chemical Synthesis Intermediate: Serves as a key building block for synthesizing more complex macrocyclic ligands and functionalized crown ethers.
• Analytical Chemistry Reagent: Utilized in ion-selective electrodes and as a mobile phase additive in chromatography for improved separation.
• Polymer Modification: Incorporated into polymer matrices to create ion-conductive materials or membranes with specific transport properties.
• Research & Development: A fundamental tool in supramolecular chemistry research for studying host-guest interactions and molecular recognition.

Basic Information

Product Name	1,4,7-Trioxa-10-Azacyclododecane
CAS No.	41775-76-2
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	1-Aza-4,7,10-trioxacyclododecane; 1-Aza-12-crown-4; 12-Crown-4, 1-aza; Aza-12-crown-4; 1,4,7,10-Tetraoxa-13-azacyclopentadecane (common misnomer, verify structure); N-Aza-12-crown-4 ether; 1-Nitrogen-12-crown-4
EINECS	Contact for details

Quality Control

Our 1,4,7-Trioxa-10-Azacyclododecane is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. Certificates of Analysis (COA) documenting purity, identity, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.