Description

18-Crown-6 (CAS NO 17455-13-9) is a highly versatile and widely used macrocyclic polyether, known for its exceptional ability to selectively bind potassium and other alkali metal cations. This property makes it an indispensable phase-transfer catalyst and complexing agent in a variety of synthetic and analytical processes. It is a critical reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over reaction pathways and ion transport is required.

Application

• Phase-Transfer Catalysis (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Cation Complexation & Masking: Selectively binds to potassium ions, used to solubilize salts in non-polar solvents and mask cation interference in analytical chemistry.
• Chemical Synthesis: Employed in the synthesis of complex molecules, including pharmaceuticals, fine chemicals, and specialty polymers.
• Electrolyte Additive: Used in battery research to modify electrolyte properties and improve ion transport.
• Sensor Technology: Acts as an ionophore in the fabrication of ion-selective electrodes (ISEs) for potassium detection.
• Separation Science: Utilized in chromatographic techniques and membrane transport studies for selective ion separation.

Basic Information

Product Name	18-Crown-6
CAS No.	17455-13-9
Molecular Formula	C12H24O6
Molecular Weight	264.32 g/mol
Synonyms	1,4,7,10,13,16-Hexaoxacyclooctadecane; 18-Crown-6 Ether; 1,4,7,10,13,16-Hexaoxacyclooctadecane; [18]Crown-6; 18-C-6; Hexaethylene glycol cyclic ether; Cyclic hexaethylene glycol ether; Crown ether 18C6
EINECS	241-471-5

Quality Control

Our 18-Crown-6 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, appearance, and moisture content. Our quality management system is designed to meet the rigorous demands of research and industrial applications, ensuring reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	37 - 40 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.