Description

1,1-Difluoroacetylacetone is a versatile fluorinated β-diketone building block, prized for its unique reactivity and ability to introduce difluoromethyl groups into complex molecular architectures. Its high volatility and compatibility with strong acid/organic solvent systems make it a critical reagent for advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel fluorinated compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing difluoromethyl motifs, which can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine substitution is crucial for activity and environmental profile.
• Ligand Precursor in Catalysis: Serves as a precursor for chelating ligands in transition metal catalysis, enabling more efficient and selective chemical transformations.
• Fluorinated Polymer & Material Science: Employed in the synthesis of specialty monomers for fluoropolymers and advanced materials with specific thermal, chemical, or surface properties.
• Coordination Chemistry & Metal Complexes: Acts as a versatile ligand for forming stable complexes with various metals, useful in analytical chemistry and material design.
• Organic Synthesis Reagent: A valuable fluorinating agent and synthon for constructing complex heterocycles and other fluorinated organic molecules in research and development.

Basic Information

Product Name	1,1-Difluoroacetylacetone
CAS No.	41739-23-5
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	1,1-Difluoro-2,4-pentanedione; 1,1-Difluoroacetylacetone; 4,4-Difluoro-2,4-pentanedione; 4,4-Difluoroacetylacetone; 1,1-Difluoro-2,4-dioxopentane; DFAA; 1,1-Difluoropentane-2,4-dione
EINECS	Contact for details

Quality Control

Our 1,1-Difluoroacetylacetone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.