Description

Diethyl 2-Cyclobutylidenemalonate is a versatile malonate ester derivative featuring a reactive cyclobutylidene moiety, making it a valuable building block in advanced organic synthesis. Its structure is pivotal for constructing complex molecular frameworks, particularly in the development of pharmaceuticals and fine chemicals. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce strained ring systems or functionalized cyclobutane derivatives into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing strained carbocyclic or heterocyclic ring systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific cyclic structural motifs.
• Material Science Monomer: Serves as a specialty monomer or cross-linking agent in the development of polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, [2+2] cycloadditions, and other cyclization strategies to construct complex organic molecules in academic and industrial R&D.
• Flavor & Fragrance Ingredient Synthesis: Utilized as an intermediate for creating specific ester compounds that contribute to complex aroma and flavor profiles.

Basic Information

Item	Details
Product Name	Diethyl 2-Cyclobutylidenemalonate
CAS No.	41589-41-7
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	Diethyl (2-cyclobutylidene)malonate; Diethyl cyclobutylidenemalonate; 2-Cyclobutylidenemalonic Acid Diethyl Ester; Propanedioic acid, 2-cyclobutylidene-, 1,3-diethyl ester; Malonic acid, cyclobutylidene-, diethyl ester; Diethyl cyclobutylidenepropanedioate
EINECS	Contact for details

Quality Control

Our Diethyl 2-Cyclobutylidenemalonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.