Description

(3S)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-6α-Hydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(3H)-One is a complex, stereochemically defined furanone derivative with significant synthetic utility. This compound serves as a versatile chiral building block and intermediate for the synthesis of more complex natural product analogs and biologically active molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel drug candidates, particularly for complex target molecules.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective chemical reactions to construct molecules with specific 3D configurations.
• Natural Product Analog Synthesis: Building block for the semi-synthesis or total synthesis of terpenoid and steroidal natural product analogs.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Contract Research: Used in university and CRO laboratories for methodological studies in organic and medicinal chemistry.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing synthetic routes in pilot plants.

Basic Information

Item	Details
Product Name	(3S)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-6α-Hydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(3H)-One
CAS No.	41410-55-3
Molecular Formula	C₁₇H₂₆O₃
Molecular Weight	278.39 g/mol
Synonyms	6α-Hydroxy-3,5aα,9-trimethyl-2,3,3aβ,4,5,5a,6,7,8,9bα-decahydronaphtho[1,2-b]furan-2-one; (3S,3aR,5aS,6R,9bR)-6-Hydroxy-3,5a,9-trimethyl-3a,4,5,5a,6,7,8,9b-octahydronaphtho[1,2-b]furan-2(3H)-one; 6α-Hydroxy-3,5aα,9-trimethyldodecahydronaphtho[1,2-b]furan-2-one; A chiral furanone lactone intermediate.
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ,4,5,5A,6,7,8,9Bα-Octahydro-6α-Hydroxy-3,5Aα,9-Trimethylnaphtho[1,2-B]Furan-2(3H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment. We can support development projects with custom purity grades, including research and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]₂₀ᴅ	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.