Description

5-Iodo-1,2,3-Trimethylbenzene is a high-purity, halogenated aromatic compound serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the iodine substituent, which acts as an excellent leaving group and facilitates subsequent cross-coupling reactions, such as Suzuki or Heck couplings, to construct more complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex aryl-aryl bond formations.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trimethylbenzene scaffold provides specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed coupling reactions (e.g., Suzuki, Stille, Sonogashira) to create biaryl and other conjugated systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where halogenated aromatic compounds are required.

Basic Information

Product Name	5-Iodo-1,2,3-Trimethylbenzene
CAS No.	41381-34-4
Molecular Formula	C9H11I
Molecular Weight	246.09 g/mol
Synonyms	1,2,3-Trimethyl-5-iodobenzene; 5-Iodo-1,2,3-trimethylbenzene; 3,4,5-Trimethyliodobenzene; 5-Iodopseudocumene; Pseudocumene, 5-iodo-; Iodopseudocumene
EINECS	Contact for details

Quality Control

Our 5-Iodo-1,2,3-Trimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.