Description

Histamine, n-Acetyl-5-Fluoro- is a fluorinated derivative of acetylhistamine, a modified biogenic amine of significant research interest. This compound serves as a crucial advanced pharmaceutical intermediate and a specialized building block in medicinal chemistry. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel histamine receptor-targeting drugs and fluorinated bioactive molecules.
• Biochemical Research: Used as a standard or reagent in studies investigating fluorinated histamine metabolism, enzyme inhibition, and receptor binding assays.
• Medicinal Chemistry: Serves as a specialized scaffold for structure-activity relationship (SAR) studies to develop new anti-allergy or neuroactive compounds.
• Diagnostic Agent Development: Potential building block for developing fluorinated tracers or probes used in imaging techniques.
• Academic & Industrial R&D: Employed in exploratory research within universities and corporate labs focusing on fluorinated heterocycles and amine chemistry.

Basic Information

Product Name	Histamine, n-Acetyl-5-Fluoro-
CAS No.	41366-99-8
Molecular Formula	C7H10FN3O
Molecular Weight	171.17 g/mol
Synonyms	5-Fluoro-N-acetylhistamine; N-Acetyl-5-fluorohistamine; 1-[2-(5-Fluoro-1H-imidazol-4-yl)ethyl]ethanone; Nα-Acetyl-5-fluorohistamine; 5-Fluoro-Nα-acetylhistamine; N-Acetyl-5-fluoro-1H-imidazole-4-ethanamine; 5-Fluoro-acetylhistamine
EINECS	Contact for details

Quality Control

Our Histamine, n-Acetyl-5-Fluoro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation (IR, NMR), and residual solvent analysis, to ensure it meets rigorous research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.