Description

Methyl 2-O,3-O:4-O,6-o-Bis(Phenylboranediyl)-α-D-Mannopyranoside CAS NO 41356-07-4 is a sophisticated, organoboron-protected carbohydrate derivative, specifically a mannopyranoside with phenylboronate ester groups. This compound is critically important as a key chiral intermediate and protecting group reagent in advanced synthetic organic chemistry, enabling precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex glycoconjugates, nucleoside analogs, and other bioactive molecules where selective manipulation of sugar hydroxyl groups is required.

Application

• Intermediate in Nucleoside & Carbohydrate Drug Synthesis: Serves as a crucial building block for creating antiviral and anticancer nucleoside analogs with modified sugar moieties.
• Chiral Auxiliary & Ligand Precursor: Used in asymmetric synthesis and as a precursor for boron-containing ligands in catalysis.
• Glycoconjugate Research: Enables the controlled synthesis of oligosaccharides and glycopeptides for biochemical and immunological studies.
• Protecting Group Strategy in Organic Synthesis: The phenylboranediyl groups provide orthogonal protection for specific hydroxyls on sugar rings during multi-step syntheses.
• Development of Boron Neutron Capture Therapy (BNCT) Agents: Potential use as a precursor in designing boron-carrier molecules for targeted cancer therapies.
• Chemical Biology Probes: Utilized in the development of tools to study glycosylation processes and carbohydrate-protein interactions.

Basic Information

Item	Details
Product Name	Methyl 2-O,3-O:4-O,6-o-Bis(Phenylboranediyl)-α-D-Mannopyranoside
CAS No.	41356-07-4
Molecular Formula	C19H21B2O6
Molecular Weight	369.99 g/mol
Synonyms	Methyl 2,3:4,6-Bis-O-(phenylboranediyl)-α-D-mannopyranoside; Methyl α-D-Mannopyranoside 2,3:4,6-Bis(phenylboronate); Phenylboronic Acid Methyl α-D-Mannopyranoside Cyclic Ester; 2,3:4,6-Di-O-phenylboranyl-α-D-methylmannoside; α-D-Methyl Mannopyranoside 2,3:4,6-Bis(phenylboronate); CAS 41356-07-4
EINECS	Contact for details

Quality Control

Our high-purity organoboron intermediates are manufactured under strict quality systems. Each batch is characterized and tested using advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and development traceability requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent hydrolysis of the boronate ester groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.