Description

Erythromycin Ethylsuccinate is a macrolide antibiotic ester, specifically the ethylsuccinate salt of erythromycin. This formulation is crucial for enhancing the solubility and bioavailability of the active pharmaceutical ingredient, making it suitable for oral dosage forms. It is primarily required by pharmaceutical manufacturers for the production of pediatric suspensions, tablets, and other formulations to treat a wide range of bacterial infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of oral antibiotic formulations.
• Pediatric Suspensions: Key component in pleasant-tasting, easy-to-administer liquid antibiotic medicines for children.
• Tablet and Capsule Production: Used in solid oral dosage forms for systemic antibiotic therapy.
• Veterinary Pharmaceuticals: Incorporated into medicated feeds and treatments for bacterial infections in animals.
• Research & Development: Serves as a reference standard and raw material in pharmaceutical R&D labs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for generic drug production.

Basic Information

Product Name	Erythromycin Ethylsuccinate
CAS No.	41342-53-4
Molecular Formula	C43H75NO16
Molecular Weight	862.06 g/mol
Synonyms	Erythromycin Ethyl Succinate; Erythromycin 2'-Ethylsuccinate; EryPed; E.E.S.; Erythrocin Ethyl Succinate; Abbott-40611; Erythromycin 8-Ethylsuccinate; Erythromycin Monoethylsuccinate
EINECS	255-291-1

Quality Control

Our Erythromycin Ethylsuccinate is manufactured under strict quality systems. It is typically tested for compliance with major pharmacopeial standards such as USP, EP, and BP. Each batch undergoes rigorous analytical testing including assay, impurity profiling, and microbiological examination. A comprehensive Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation. The original container should be kept sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Meets pharmacopeial requirements
Microbial Limits	Meets pharmacopeial requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.