Description

(20S)-3β,20-Bis(Trimethylsilyloxy)Pregn-4-En-17-Ol is a high-purity, silyl-protected steroid derivative, specifically designed as a critical synthetic intermediate. This compound matters for its role in enabling complex organic syntheses, particularly in the production of specialized pharmaceutical agents and advanced research chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the targeted synthesis of steroid-based drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used as a protected precursor in medicinal chemistry for exploring structure-activity relationships (SAR) and developing new drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid derivatives under controlled conditions.
• Biochemical Research: Utilized in studies investigating steroid hormone pathways, receptor binding, and metabolic processes.

Basic Information

Product Name	(20S)-3β,20-Bis(Trimethylsilyloxy)Pregn-4-En-17-Ol
CAS No.	41259-41-0
Molecular Formula	C29H54O3Si2
Molecular Weight	506.91 g/mol
Synonyms	Pregn-4-ene-3β,17,20-triol, 3,20-bis(trimethylsilyl) ether, (20S)-; 3β,20α-Bis(trimethylsilyloxy)pregn-4-en-17-ol; (20S)-3β,20-Bis(trimethylsiloxy)pregn-4-en-17-ol; 41259-41-0; 3,20-Bis-O-(trimethylsilyl)-17-hydroxypregn-4-ene; 17-Hydroxypregn-4-ene-3,20-diyl bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our (20S)-3β,20-Bis(Trimethylsilyloxy)Pregn-4-En-17-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.