Description

Ethyl 1-Hydroxycyclobutane-1-Carboxylate is a versatile chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its unique structure, featuring both a hydroxyl and an ester group on a strained cyclobutane ring, makes it a critical precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of potential drug candidates, including protease inhibitors, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or specialty polymers with unique thermal or mechanical properties derived from the cyclobutane scaffold.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex odorants and flavor compounds with specific stereochemical requirements.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Ethyl 1-Hydroxycyclobutane-1-Carboxylate
CAS No.	41248-22-0
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	1-Hydroxycyclobutane-1-carboxylic Acid Ethyl Ester; Ethyl 1-Hydroxycyclobutanecarboxylate; 1-Hydroxycyclobutanecarboxylic Acid Ethyl Ester; Ethyl Cyclobutylglycolate; (±)-Ethyl 1-Hydroxycyclobutanecarboxylate; Ethyl 1-Hydroxy-1-cyclobutanecarboxylate; 1-Carbethoxy-1-hydroxycyclobutane
EINECS	Contact for details

Quality Control

Our Ethyl 1-Hydroxycyclobutane-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, GC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (20°C, D line)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.