Description

2-Bromo-2-Methylbutyric Acid is a versatile halogenated carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the sterically hindered 2-bromo-2-methylbutyryl moiety, a key functional group for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and novel materials. Its reliable quality and consistent performance make it a trusted reagent for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring quaternary carbon centers or specific steric profiles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate halogenated acid functionalities.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the production of specialized polymers and coatings with tailored properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions, esterifications, and amide couplings to introduce the 2-bromo-2-methylbutyryl group.
• Ligand and Catalyst Preparation: Useful for synthesizing novel ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Chemical Research & Development: A valuable tool in medicinal chemistry and material science R&D for exploring new chemical entities and functional materials.

Basic Information

Product Name	2-Bromo-2-Methylbutyric Acid
CAS No.	41242-50-6
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	2-Bromo-2-methylbutanoic acid; α-Bromo-α-methylbutyric acid; 2-Methyl-2-bromobutanoic acid; NSC 401121; Butanoic acid, 2-bromo-2-methyl-; 2-Bromo-2-methylbutyric acid; 2-Bromo-2-methyl-butyric acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis, supporting your process reliability and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.470 - 1.480
Density (g/mL at 20°C)	1.45 - 1.55

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.