Description

16-Diazoestrone is a specialized diazo derivative of the natural estrogen, estrone, with the CAS number 41164-31-2. This compound is a valuable synthetic intermediate, prized for its reactive diazo functional group which enables precise chemical modifications in complex organic syntheses. It is primarily utilized by research institutions and pharmaceutical development teams working on steroid chemistry, novel drug discovery, and the synthesis of biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for studying steroid hormone analogs and their biological activities.
• Organic Synthesis: Serves as a precursor for creating complex molecular architectures via diazo transfer and cyclization reactions.
• Bioconjugation Probes: Potential use in developing labeled compounds or probes for biochemical and diagnostic research.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	16-Diazoestrone
CAS No.	41164-31-2
Molecular Formula	C₁₈H₂₂N₂O₂
Molecular Weight	298.38 g/mol
Synonyms	16-Diazoestrone; Estrone, 16-diazo-; 16-Diazoestra-1,3,5(10)-trien-3-ol-17-one; 16-Diazo-O-estrone; 16-Diazo-17-oxoestra-1,3,5(10)-trien-3-ol
EINECS	Contact for details

Quality Control

Our 16-Diazoestrone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.