Description

(R)-3,4-Dihydro-3-Hydroxy-2,2-Dimethyl-2H-Naphtho[1,2-B]Pyran-5,6-Dione is a high-purity chiral naphthoquinone derivative with significant synthetic utility. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Asymmetric Synthesis: Utilized as a building block for constructing complex, stereochemically defined molecules due to its rigid naphthoquinone framework and chiral center.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with enhanced activity and selectivity.
• Material Science: Potential monomer or precursor for functional organic materials and dyes, leveraging its quinone structure.
• Academic & R&D: Serves as a standard or starting material in methodological studies and total synthesis projects within university and corporate laboratories.

Basic Information

Item	Details
Product Name	(R)-3,4-Dihydro-3-Hydroxy-2,2-Dimethyl-2H-Naphtho[1,2-B]Pyran-5,6-Dione
CAS No.	41135-46-0
Molecular Formula	C₁₅H₁₄O₄
Molecular Weight	258.27 g/mol
Synonyms	(R)-3-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-naphtho[1,2-b]pyran-5,6-dione; (R)-Lapachol derivative; (R)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-2H-benzo[g]chromene-5,10-dione; (R)-β-Lapachone analogue; (R)-2,2-Dimethyl-3,4-dihydro-2H-naphtho[1,2-b]pyran-3-ol-5,6-dione; (R)-Naphtho[1,2-b]pyran-5,6-dione, 3,4-dihydro-3-hydroxy-2,2-dimethyl-, (3R)-; (3R)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione
EINECS	Contact for details

Quality Control

Our (R)-3,4-Dihydro-3-Hydroxy-2,2-Dimethyl-2H-Naphtho[1,2-B]Pyran-5,6-Dione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for chiral purity and chemical assay, NMR, and IR for structural confirmation, to ensure compliance with research and industrial grade specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.