Description

Isopropyl 4-Chloro-3-oxobutanoate is a versatile organic ester building block, specifically an isopropyl ester of a chlorinated β-keto acid. This compound matters as a key synthetic intermediate, prized for its reactive β-keto ester and chloro functionalities which enable diverse chemical transformations. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular scaffolds, including heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for molecular diversification.
• Chemical Research & Development: Serves as a versatile starting material in organic synthesis for academic and industrial R&D, enabling studies on Claisen condensations, alkylations, and cyclization reactions.
• Fine Chemical Production: Employed in the manufacture of specialty and performance chemicals where specific chlorinated keto-ester motifs are required.
• Material Science Precursor: Potential use in synthesizing monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Product Name	Isopropyl 4-Chloro-3-oxobutanoate
CAS No.	41051-20-1
Molecular Formula	C7H11ClO3
Molecular Weight	178.62 g/mol
Synonyms	4-Chloro-3-oxobutanoic acid isopropyl ester; Isopropyl 4-chloroacetoacetate; 1-Methylethyl 4-chloro-3-oxobutanoate; 4-Chloroacetoacetic acid isopropyl ester; 3-Oxobutanoic acid, 4-chloro-, 1-methylethyl ester; Acetoacetic acid, 4-chloro-, isopropyl ester; Isopropyl β-chloroacetoacetate
EINECS	Contact for details

Quality Control

Our Isopropyl 4-Chloro-3-oxobutanoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and technical compliance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.