Description

Diethyl n-Formyl-Aminomethyl Phosphonate is a specialized organophosphorus compound with a unique formylaminomethyl functional group. This structure makes it a valuable key intermediate and building block in advanced organic synthesis, particularly for the preparation of complex molecules. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical R&D and manufacturing sectors seeking to incorporate phosphonate or amino acid-like motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules containing phosphonate groups.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, plant growth regulators, and other crop protection agents with enhanced properties.
• Peptidomimetic Research: Serves as a key component in the design and synthesis of peptidomimetics, where it can mimic the transition state of peptide hydrolysis or act as a non-hydrolyzable amino acid analog.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphonate-containing ligands for metal catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized in the creation of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Material Science: Acts as a monomer or functional additive in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	Diethyl n-Formyl-Aminomethyl Phosphonate
CAS No.	41003-95-6
Molecular Formula	C6H14NO4P
Molecular Weight	195.16 g/mol
Synonyms	Diethyl (Formylamino)methylphosphonate; (Formylaminomethyl)phosphonic Acid Diethyl Ester; Diethyl N-Formylaminomethylphosphonate; Phosphonic Acid, (Formylaminomethyl)-, Diethyl Ester; Aminomethylphosphonic Acid Diethyl Ester N-Formyl Derivative; NSC 163063
EINECS	Contact for details

Quality Control

Our Diethyl n-Formyl-Aminomethyl Phosphonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP requirements for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.