Description

Methyl (2S,3S)-3-Phenyloxirane-2-Carboxylate is a high-purity chiral epoxide building block of significant importance in asymmetric synthesis. This compound serves as a versatile and stereochemically defined intermediate for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is critical. Our supply ensures consistent quality and reliable availability for your most demanding synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development and screening of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & Process Chemistry: A valuable tool for studying ring-opening reactions and for scaling up stereoselective synthetic routes in process development.

Basic Information

Product Name	Methyl (2S,3S)-3-Phenyloxirane-2-Carboxylate
CAS No.	40956-18-1
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	Methyl (2S,3S)-(-)-3-Phenylglycidate; (2S,3S)-Methyl 3-phenylglycidate; (-)-Methyl trans-3-Phenylglycidate; (2S,3S)-(-)-Methyl 2,3-Epoxy-3-phenylpropionate; trans-Methyl 3-phenylglycidate; Methyl (2S,3S)-2,3-Epoxy-3-phenylpropanoate; Phenylglycidic Acid Methyl Ester, (2S,3S)-(-)-form
EINECS	Contact for details

Quality Control

Our Methyl (2S,3S)-3-Phenyloxirane-2-Carboxylate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC to ensure high enantiomeric excess (ee) and chemical purity. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.