Description

4'-Fluoro-4-Iodobutyrophenone is a high-purity, synthetically valuable halogenated aromatic ketone building block. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical intermediates sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated and iodinated aromatic systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the unique halogen pattern influences biological activity.
• Ligand & Catalyst Synthesis: Serves as a starting material for creating specialized ligands and organocatalysts used in cross-coupling and other metal-mediated reactions.
• Material Science Precursor: Employed in the research and development of advanced organic materials, including liquid crystals and photoactive compounds.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to its halogen handles.

Basic Information

Product Name	4'-Fluoro-4-Iodobutyrophenone
CAS No.	40862-32-6
Molecular Formula	C10H10FIO
Molecular Weight	292.09 g/mol
Synonyms	1-(4-Fluorophenyl)-4-iodobutan-1-one; 4-Iodo-1-(4-fluorophenyl)butan-1-one; 4'-Fluoro-γ-iodobutyrophenone; 4-Fluoro-4'-iodobutyrophenone; p-Fluoro-γ-iodobutyrophenone; Butyrophenone, 4'-fluoro-4-iodo-; 4-Iodobutyl 4-fluorophenyl ketone
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-4-Iodobutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.