Description

Benzene, 1-Bromo-4-(1-Methylcyclopropyl)- CAS NO 40780-08-3 is a specialized brominated aromatic compound featuring a unique 1-methylcyclopropyl substituent, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its core value proposition lies in providing a structurally defined building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research where the cyclopropyl moiety is a key pharmacophore. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors who require high-purity, structurally complex intermediates for synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating cyclopropyl groups for metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromine atom allows for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or advanced polymers with tailored electronic properties.
• Cross-Coupling Reactions: The aryl bromide functionality makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Benzene, 1-Bromo-4-(1-Methylcyclopropyl)-
CAS No.	40780-08-3
Molecular Formula	C10H11Br
Molecular Weight	211.10 g/mol
Synonyms	1-Bromo-4-(1-methylcyclopropyl)benzene; 4-Bromo-1-(1-methylcyclopropyl)benzene; p-(1-Methylcyclopropyl)bromobenzene; (1-Methylcyclopropyl)-4-bromobenzene; 40780-08-3; 1-Methylcyclopropyl-4-bromobenzene; 4-Bromo-α-methylcyclopropylbenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-4-(1-Methylcyclopropyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive and should be stored away from light. Keep container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.