Description

2-(Trifluoromethyl)Sulfonylaminoethanol is a specialized organofluorine building block featuring a reactive aminoethanol group and a trifluoromethylsulfonyl moiety. This compound is valued for its role in introducing the highly electronegative and lipophilic trifluoromethanesulfonamide (triflyl) group into target molecules, which can significantly alter their physical and biological properties. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring the triflyl group to enhance metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethylsulfonyl group contributes to efficacy and environmental persistence profiles.
• Material Science: Serves as a monomer or modifier in the production of specialty polymers and coatings, imparting unique surface properties, chemical resistance, or optical characteristics.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Fluorine Chemistry Research: A versatile reagent for academic and industrial R&D focused on exploring new fluorinated compounds and their applications.

Basic Information

Product Name	2-(Trifluoromethyl)Sulfonylaminoethanol
CAS No.	40630-40-8
Molecular Formula	C₃H₆F₃NO₃S
Molecular Weight	193.15 g/mol
Synonyms	2-[(Trifluoromethyl)sulfonyl]aminoethanol; N-(2-Hydroxyethyl)trifluoromethanesulfonamide; 2-(Trifluoromethanesulfonamido)ethanol; 2-(Triflylamino)ethanol; Ethanol, 2-[[(trifluoromethyl)sulfonyl]amino]-; 2-Hydroxyethyl trifluoromethyl sulfonamide; Trifluoromethanesulfonic acid 2-hydroxyethylamide
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Sulfonylaminoethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.