Description

D-(+)-Norephedrine Hydrochloride is a high-purity chiral intermediate and active pharmaceutical ingredient (API) of significant commercial and research importance. Its defined stereochemistry and hydrochloride salt form ensure consistent reactivity and stability, making it a critical building block for advanced synthesis. This compound is essential for manufacturers and research institutions in the pharmaceutical, fine chemical, and analytical sectors requiring a reliable source of a specific enantiomer for process development and quality control.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of adrenergic agents, decongestants, and other therapeutic compounds.
• Chemical Reference Standard: Used for method development, calibration, and quality assurance in analytical laboratories (HPLC, GC, LC-MS).
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in the production of enantiomerically pure substances.
• Biochemical Research: Utilized in studies of neurotransmitter pathways, receptor binding assays, and metabolic processes.
• Fine Chemical Synthesis: Building block for creating complex molecules in agrochemical and specialty chemical research.

Basic Information

Product Name	D-(+)-Norephedrine Hydrochloride
CAS No.	40626-29-7
Molecular Formula	C9H14ClNO
Molecular Weight	187.66 g/mol
Synonyms	(1R,2S)-2-Amino-1-phenyl-1-propanol hydrochloride; D-Norephedrine HCl; (+)-Norephedrine hydrochloride; (R*,S*)-α-(1-Aminoethyl)benzyl alcohol hydrochloride; d-threo-2-Amino-1-phenyl-1-propanol hydrochloride; Phenylpropanolamine impurity D; (1R,2S)-Norephedrine hydrochloride
EINECS	Contact for details

Quality Control

Our D-(+)-Norephedrine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.