Description

4-(2-Bromoethyl)-Acetophenone is a versatile brominated aromatic ketone intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active pharmaceutical ingredients (APIs), ligands, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring phenethylamine or substituted acetophenone backbones.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators where the bromoethyl side chain enables further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers with specific electronic or photonic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	4-(2-Bromoethyl)-Acetophenone
CAS No.	40422-73-9
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	1-[4-(2-Bromoethyl)phenyl]ethanone; 4'-Bromoethylacetophenone; 2-(4-Acetylphenyl)ethyl bromide; p-(2-Bromoethyl)acetophenone; 4-Acetylphenethyl bromide; (4-Acetylphenyl)ethyl bromide; 1-(4-(2-Bromoethyl)phenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoethyl)-Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.