Description

3'-Bromo-2-Phenylacetophenone is a versatile brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a phenylacetophenone backbone, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aryl-alkyl ketone frameworks.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents that require halogenated aromatic components.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport materials and host materials in OLED displays and lighting.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Fine Chemical and Dye Intermediate: Employed in the production of complex dyes, pigments, and other high-value specialty chemicals.
• Academic and R&D: A valuable reagent for methodological studies in cross-coupling reactions and novel ring-forming transformations in university and corporate research labs.

Basic Information

Product Name	3'-Bromo-2-Phenylacetophenone
CAS No.	40396-53-0
Molecular Formula	C14H11BrO
Molecular Weight	275.14 g/mol
Synonyms	2-Phenyl-3'-bromoacetophenone; 1-(3-Bromophenyl)-2-phenylethan-1-one; 3'-Bromodeoxybenzoin; 3-Bromobenzyl Phenyl Ketone; (3-Bromophenyl)(phenyl)methanone; α-Phenyl-3'-bromoacetophenone; β-Bromobenzyl Phenyl Ketone; 3-Bromophenyl Phenyl Ketone
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2-Phenylacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	75 - 79 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.