Description

2-Bromo-4-Chloro-5-Nitrotoluene is a halogenated nitroaromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for research and development chemists and production facilities specializing in active pharmaceutical ingredients (APIs), crop protection agents, and specialty dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with halogenated aromatic cores.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where the bromo, chloro, and nitro functional groups impart specific biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for producing complex azo dyes and other colored compounds.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro and halogen groups make it reactive in SNAr reactions for further functionalization.

Basic Information

Product Name	2-Bromo-4-Chloro-5-Nitrotoluene
CAS No.	40371-64-0
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	1-Bromo-2-chloro-4-methyl-5-nitrobenzene; Toluene, 2-bromo-4-chloro-5-nitro-; 5-Nitro-2-bromo-4-chlorotoluene; 4-Chloro-2-bromo-5-nitrotoluene; 2-Bromo-4-chloro-5-nitro-1-methylbenzene; 2-Bromo-4-chloro-5-nitro-toluene; 2-Bromo-4-chloro-5-nitromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-5-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.