Description

2-Bromo-1-(6-Methylpyridin-3-yl)ethanone is a versatile brominated ketone building block featuring a pyridine core. This compound is valued for its reactivity as an alkylating agent and its utility in constructing complex heterocyclic scaffolds. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for use in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Synthesis Building Block: Employed in organic synthesis for the introduction of the 2-bromoacetyl functional group onto pyridine systems via nucleophilic substitution reactions.
• Material Science Precursor: Serves as a starting material for the preparation of specialized ligands, polymers, or functionalized materials.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	2-Bromo-1-(6-Methylpyridin-3-yl)ethanone
CAS No.	40337-65-3
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	2-Bromo-1-(6-methyl-3-pyridinyl)ethanone; 2-Bromo-1-(6-methylpyridin-3-yl)ethan-1-one; 3-Acetyl-6-methylpyridinium bromide (ketone form); 1-(6-Methyl-3-pyridinyl)-2-bromoethanone; 2-Bromo-1-(6-methyl-3-pyridyl)ethanone; α-Bromo-6-methylnicotinyl ketone; 2-Bromo-6-methylnicotinyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(6-Methylpyridin-3-yl)ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.