Description

1-(3-Bromoprop-1-Yn-1-Yl)-4-Fluorobenzene CAS NO 40274-29-1 is a high-purity, specialized organic building block featuring both a bromoalkyne and a fluorinated aromatic ring, making it a versatile intermediate for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of novel active compounds. It is primarily utilized by the pharmaceutical, agrochemical, and advanced materials industries for applications in medicinal chemistry, ligand synthesis, and the creation of functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly for introducing fluorinated and alkyne-functionalized motifs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the fluorobenzene and reactive bromoalkyne groups.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed in click chemistry applications (e.g., CuAAC reactions) for bioconjugation and probe development due to its terminal alkyne functionality.
• Ligand & Catalyst Synthesis: A precursor for creating sophisticated ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for exploratory organic synthesis and methodology development in research laboratories.

Basic Information

Product Name	1-(3-Bromoprop-1-Yn-1-Yl)-4-Fluorobenzene
CAS No.	40274-29-1
Molecular Formula	C9H6BrF
Molecular Weight	213.05 g/mol
Synonyms	4-Fluoro-1-(3-bromoprop-1-yn-1-yl)benzene; 1-Bromo-3-(4-fluorophenyl)propyne; 3-(4-Fluorophenyl)prop-2-yn-1-yl bromide; 4-Fluorophenyl propargyl bromide; p-Fluorophenyl propargyl bromide; 1-(3-Bromopropynyl)-4-fluorobenzene; 40274-29-1
EINECS	Contact for details

Quality Control

Our 1-(3-Bromoprop-1-Yn-1-Yl)-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.