Description

1,2-Dibromo-1,2,2-Trifluoro-1-Phenylethane is a specialized halogenated organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring both bromine and fluorine substituents on an ethane backbone, makes it a valuable reagent for introducing fluorinated motifs and for use in cross-coupling reactions. This high-purity intermediate is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and functional materials. The compound, with CAS No. 40193-72-4, is supplied under stringent quality controls to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and fluorinated coatings with unique surface properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a source of fluorinated and brominated carbon units in complex molecule assembly.
• Liquid Crystal & OLED Materials: A precursor in the manufacture of fluorinated components for electronic display and lighting technologies.
• Research & Development: A critical tool for medicinal chemists and process chemists exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	1,2-Dibromo-1,2,2-Trifluoro-1-Phenylethane
CAS No.	40193-72-4
Molecular Formula	C8H5Br2F3
Molecular Weight	325.93 g/mol
Synonyms	α,β-Dibromo-β,β,β-trifluorophenylethane; 1-Phenyl-1,2-dibromo-2,2,2-trifluoroethane; Phenylethane, 1,2-dibromo-1,2,2-trifluoro-; DBTPE; 1,2-Dibromo-1,2,2-trifluoroethylbenzene; (1,2-Dibromo-2,2,2-trifluoroethyl)benzene; Benzene, (1,2-dibromo-2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-1,2,2-Trifluoro-1-Phenylethane is manufactured under a cGMP-compliant quality management system to ensure the highest standards of purity and traceability. Each batch is rigorously tested using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full documentation and compliance with REACH and other major global chemical regulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity to light, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.