Description

(3R,11As)-2,3,3Aβ,4,5,5A,5Bα,6,6A,7,8,9,9Aβ,10-Tetradecahydro-3β,5Aα,6Aα-Trimethyl-9β-Isopropyl-1H-Pentaleno[1,6A-A]-S-Indacene-11-Carboxylic Acid is a complex, high-purity diterpenoid carboxylic acid derivative with a unique pentaleno-indacene fused ring system. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold for the synthesis of novel bioactive molecules. It is essential for researchers and manufacturers in pharmaceutical development and fine chemical synthesis who require structurally defined, high-quality building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Organic Synthesis Research: Advanced starting material for exploring complex polycyclic ring systems and stereoselective transformations in academic and industrial R&D.
• Medicinal Chemistry: Core scaffold for structure-activity relationship (SAR) studies and the development of proprietary compound libraries.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(3R,11As)-2,3,3Aβ,4,5,5A,5Bα,6,6A,7,8,9,9Aβ,10-Tetradecahydro-3β,5Aα,6Aα-Trimethyl-9β-Isopropyl-1H-Pentaleno[1,6A-A]-S-Indacene-11-Carboxylic Acid
CAS No.	40184-98-3
Molecular Formula	C28H40O2
Molecular Weight	408.62 g/mol
Synonyms	11-Carboxy-3β,5aα,6aα-trimethyl-9β-isopropylperhydropentaleno[1,6a-a]indacene; Pentaleno[1,6a-a]indacene-11-carboxylic acid derivative; Diterpenoid carboxylic acid intermediate; (3R,11aS)-Tetradecahydro-3,5a,6a-trimethyl-9-isopropyl-1H-pentaleno[1,6a-a]indacene-11-carboxylic acid; Labdane-type diterpene acid; Advanced tricyclic diterpenoid scaffold.
EINECS	Contact for details

Quality Control

Our (3R,11As)-2,3,3Aβ,4,5,5A,5Bα,6,6A,7,8,9,9Aβ,10-Tetradecahydro-3β,5Aα,6Aα-Trimethyl-9β-Isopropyl-1H-Pentaleno[1,6A-A]-S-Indacene-11-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid nature, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.