Description

3-(2',6'-Difluorophenyl)-3-Oxopropanenitrile is a versatile fluorinated aromatic ketone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of fluorine atoms and a reactive cyanoacetyl group, enabling precise molecular construction for high-value applications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers and polymers for specialty plastics, coatings, and electronic materials requiring fluorinated components.
• Chemical Biology Probes: Useful for constructing molecular probes and tags that leverage fluorine's unique NMR properties for imaging and diagnostic applications.

Basic Information

Item	Details
Product Name	3-(2',6'-Difluorophenyl)-3-Oxopropanenitrile
CAS No.	40017-76-3
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	2',6'-Difluorodesoxybenzoin Cyanohydrin; 2,6-Difluorophenyl Cyanomethyl Ketone; 3-Oxo-3-(2,6-difluorophenyl)propanenitrile; 2,6-Difluorobenzoylacetonitrile; (2,6-Difluorobenzoyl)acetonitrile; α-Cyano-2',6'-difluoroacetophenone; 40017-76-3
EINECS	Contact for details

Quality Control

Our 3-(2',6'-Difluorophenyl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.