Description

4-Nitrophenylglyoxal Hydrate is a specialized aromatic α-diketone derivative, serving as a versatile and highly reactive chemical building block. Its core value lies in its ability to act as a selective reagent for the modification of arginine residues in peptides and proteins, making it indispensable for advanced biochemical research and synthesis. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from proteomics to the development of novel active pharmaceutical ingredients (APIs).

Application

• Biochemical Research: Selective modification and identification of arginine residues in peptides, proteins, and enzymes for structural and functional studies.
• Proteomics & Protein Chemistry: Used as a key reagent in protein sequencing, mapping, and the study of protein-ligand interactions.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex molecules, including potential drug candidates and diagnostic agents.
• Cross-linking Agent: Facilitates the creation of cross-links in biomolecules for stabilization or conjugation purposes in bioconjugation chemistry.
• Fine Chemical Synthesis: Employed in the preparation of heterocyclic compounds, dyes, and other specialty organic materials.
• Academic & Industrial R&D: A valuable tool for investigating reaction mechanisms and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	4-Nitrophenylglyoxal Hydrate
CAS No.	4996-22-9
Molecular Formula	C8H7NO5 • xH2O
Molecular Weight	197.14 (Anhydrous basis)
Synonyms	p-Nitrophenylglyoxal Hydrate; (4-Nitrophenyl)oxoacetaldehyde Hydrate; 2-Oxo-2-(4-nitrophenyl)acetaldehyde Hydrate; 4-Nitrobenzoylformaldehyde Hydrate; Glyoxal, (4-nitrophenyl)-, Hydrate; 1-(4-Nitrophenyl)-1,2-ethanedione Hydrate
EINECS	Contact for details

Quality Control

Our 4-Nitrophenylglyoxal Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles, supporting compliance with research and development standards. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep container tightly sealed under an inert atmosphere such as nitrogen or argon to minimize oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.