Description

p-Nitrophenylglyoxal is a high-purity, specialized chemical building block and analytical reagent. This compound is valued for its reactive glyoxal moiety and the spectroscopic handle provided by the nitrophenyl group, making it a critical intermediate in advanced organic synthesis and biochemical research. It is primarily sought by professionals in pharmaceutical development, agrochemical research, and academic laboratories for synthesizing heterocyclic compounds and as a derivatization agent.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex heterocyclic structures with potential biological activity.
• Biochemical Research: Used as a derivatizing agent for the selective modification of arginine residues in peptides and proteins for analytical purposes.
• Agrochemical Synthesis: Serves as a precursor in the development of novel active ingredients for crop protection.
• Organic Synthesis: A versatile reagent for constructing diketone and quinoxaline derivatives in medicinal chemistry.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Analytical Chemistry: Employed as a standard or reagent in chromatographic and spectroscopic method development.

Basic Information

Product Name	p-Nitrophenylglyoxal
CAS No.	4974-57-6
Molecular Formula	C8H5NO5
Molecular Weight	195.13 g/mol
Synonyms	1-(4-Nitrophenyl)-1,2-ethanedione; 4-Nitrophenylglyoxal; 2-Oxo-2-(4-nitrophenyl)acetaldehyde; p-Nitrophenylethanedione; Glyoxal, (p-nitrophenyl)-; (4-Nitrophenyl)glyoxal; 4-NPG; PNPG
EINECS	225-618-6

Quality Control

Our p-Nitrophenylglyoxal is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its properties of being light-sensitive and easily oxidized, it is recommended to store the material under an inert atmosphere for long-term stability and to minimize decomposition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.