Description

Octadecyl 5-Oxo-L-Prolinate is a high-purity specialty ester derived from L-proline, designed for advanced formulation and synthesis. This compound is valued for its unique amphiphilic structure, which provides a critical balance of lipophilic and functional properties. It serves as a key intermediate and functional additive for research and industrial applications in the pharmaceutical, cosmetic, and specialty chemical sectors, where precise molecular characteristics are essential.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs, leveraging its chiral center and ester functionality.
• Cosmetic & Personal Care Formulations: Acts as a skin-conditioning agent and emollient in high-end creams, lotions, and serums due to its long alkyl chain.
• Lipid Nanoparticle (LNP) & Drug Delivery Systems: Serves as a structural component or surface modifier in advanced delivery vehicles for enhanced bioavailability.
• Bioconjugation & Chemical Biology: Provides a hydrophobic linker or protecting group in the development of probes, tags, and biomolecule conjugates.
• Specialty Surfactant & Emulsifier: Functions as a non-ionic surfactant or co-emulsifier in niche industrial and agrochemical formulations.
• Organic Synthesis & Catalysis: Employed as a chiral building block or ligand precursor in asymmetric synthesis and catalytic processes.

Basic Information

Product Name	Octadecyl 5-Oxo-L-Prolinate
CAS No.	4931-72-0
Molecular Formula	C23H43NO3
Molecular Weight	381.60 g/mol
Synonyms	Stearyl 5-Oxo-L-Prolinate; L-Pyroglutamic Acid Octadecyl Ester; 5-Oxo-L-Proline Octadecyl Ester; Octadecyl L-Pyroglutamate; 1-Octadecyl 5-Oxo-L-Prolinate; 2-Pyrrolidone-5-carboxylic Acid, Octadecyl Ester, (S)-; NSC 334365; Stearyl Pyroglutamate
EINECS	225-570-3

Quality Control

Our Octadecyl 5-Oxo-L-Prolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.