Description

3-(4-Bromophenyl)-1-(Pyrrolidin-1-Yl)Propan-1-One is a high-purity, versatile organic building block featuring a brominated phenyl group linked to a pyrrolidinyl propanone moiety. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development and optimization of novel herbicides, fungicides, and insecticides, leveraging its bromine atom for further functionalization.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies in cross-coupling reactions (e.g., Suzuki, Heck) and amide bond formation.
• Ligand & Catalyst Development: Utilized as a scaffold for creating novel ligands and organocatalysts for asymmetric synthesis.
• Life Science Research: Functions as a biochemical tool or probe in medicinal chemistry programs for hit-to-lead optimization.

Basic Information

Product Name	3-(4-Bromophenyl)-1-(Pyrrolidin-1-Yl)Propan-1-One
CAS No.	4897-53-4
Molecular Formula	C₁₃H₁₆BrNO
Molecular Weight	282.18 g/mol
Synonyms	1-(4-Bromophenyl)-3-(1-pyrrolidinyl)-1-propanone; 3-(4-Bromophenyl)-1-(pyrrolidin-1-yl)propan-1-one; 4'-Bromopropiophenone pyrrolidine enamine; 1-Propanone, 3-(4-bromophenyl)-1-(1-pyrrolidinyl)-; 3-(p-Bromophenyl)-1-(pyrrolidin-1-yl)propan-1-one; 4-Bromo-β-pyrrolidinopropiophenone; β-Pyrrolidino-4'-bromopropiophenone
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-1-(Pyrrolidin-1-Yl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.