Description

5-Bromo-1H-Benzimidazole is a halogenated benzimidazole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its versatile bromine substituent, which enables selective cross-coupling reactions and further functionalization to create complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting viral infections and certain cancers, leveraging the benzimidazole pharmacophore.
• Agrochemical Synthesis: Used in the development of new-generation fungicides and herbicides, where the bromo-benzimidazole core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized N-heterocyclic ligands used in transition metal catalysis.
• Material Science Research: Employed in the construction of organic electronic materials, such as those for OLEDs, due to its electron-deficient aromatic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Bromo-1H-Benzimidazole
CAS No.	4887-88-1
Molecular Formula	C7H5BrN2
Molecular Weight	197.03 g/mol
Synonyms	5-Bromo-1H-benzo[d]imidazole; 5-Bromobenzimidazole; 1H-Benzimidazole, 5-bromo-; 5-Bromo-benzimidazole; NSC 406901; AI3-52095; CCRIS 9351; 4887-88-1
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment. We support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	245 - 250 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.