Description

1,4'-Bipiperidine Dihydrochloride is a high-purity, versatile organic salt widely used as a key pharmaceutical intermediate and building block in chemical synthesis. Its value lies in its rigid, symmetrical bipiperidine structure, which serves as a privileged scaffold for developing bioactive molecules, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new compounds with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing novel drug candidates, libraries, and analogs for biological screening.
• Ligand and Catalyst Synthesis: Used in the preparation of complex ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Agrochemical Development: Employed as an intermediate in the research and production of advanced pesticides and herbicides.
• Fine Chemical Synthesis: Acts as a versatile precursor for creating specialty chemicals, dyes, and functional materials.
• Bioconjugation and Linker Chemistry: Utilized in the development of chemical linkers and spacers for bioconjugation applications in diagnostics and biotechnology.

Basic Information

Product Name	1,4'-Bipiperidine Dihydrochloride
CAS No.	4876-60-2
Molecular Formula	C10H22N2·2HCl
Molecular Weight	239.21 g/mol
Synonyms	1,4'-Bipiperidine dihydrochloride; 4,4'-Bipiperidine dihydrochloride; 1,1'-Bipiperidine dihydrochloride; 1,1'-Dipyperidinyl dihydrochloride; Bipiperidine dihydrochloride; 1,1'-Methylenedipiperidine dihydrochloride (common misnomer); 1,4'-Diazabicyclo[4.4.0]decane dihydrochloride; UNII-8JQ5607IO5
EINECS	Contact for details

Quality Control

Our 1,4'-Bipiperidine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Freely soluble in water, soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.