Description

2-Phenylethyl-1-Boronic Acid Diethanolamine Ester is a protected boronic acid derivative, offering enhanced stability and handling characteristics compared to its free acid form. This compound is a crucial synthetic intermediate in modern organic and medicinal chemistry, particularly valued for its role in cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for constructing biaryl and other C-C bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Used in the research and development of potential drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced pesticides and herbicides with specific activity profiles.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds on a commercial scale.

Basic Information

Product Name	2-Phenylethyl-1-Boronic Acid Diethanolamine Ester
CAS No.	4848-04-8
Molecular Formula	C₁₂H₂₀BNO₂
Molecular Weight	221.10 g/mol
Synonyms	2-Phenylethylboronic Acid Diethanolamine Ester; (2-Phenylethyl)boronic Acid Diethanolamine Ester; B-(2-Phenylethyl)boronic Acid Diethanolamine Ester; Diethanolamine (2-Phenylethyl)boronate; 2-Phenylethylboronic Acid DEA Ester; Boronic Acid, B-(2-Phenylethyl)-, compd. with 2,2'-Iminodiethanol (1:1); 4848-04-8; Phenethylboronic Acid Diethanolamine Complex
EINECS	Contact for details

Quality Control

Our 2-Phenylethyl-1-Boronic Acid Diethanolamine Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request, supporting your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.