Description

3-(Thiophen-2-Yl)Prop-2-Ynoic Acid is a specialized organic building block featuring a thiophene ring conjugated to a propiolic acid moiety. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical R&D teams for constructing novel heterocyclic compounds and functional materials. The compound's reactivity profile offers versatile pathways for creating targeted molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of conductive polymers and organic semiconductors for electronic devices.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile starting material for academic and industrial research into new organic reactions and heterocyclic chemistry.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals used in flavors, fragrances, and advanced performance materials.

Basic Information

Product Name	3-(Thiophen-2-Yl)Prop-2-Ynoic Acid
CAS No.	4843-44-1
Molecular Formula	C7H4O2S
Molecular Weight	152.17 g/mol
Synonyms	2-Propynoic acid, 3-(2-thienyl)-; 3-(2-Thienyl)propiolic acid; 3-(Thiophen-2-yl)propiolic acid; 2-Thiophenepropiolic acid; Thiophene-2-propiolic acid; 3-(2-Thienyl)-2-propynoic acid; T2PA; 4843-44-1 (CAS)
EINECS	Contact for details

Quality Control

Our production of 3-(Thiophen-2-Yl)Prop-2-Ynoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.