Description

[R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-Methoxyphenyl)-1-Propanone is a high-purity chiral aromatic ketone compound, recognized for its specific stereochemistry and functional groups. This compound matters as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the production of complex molecules with precise stereochemical control. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Serves as a building block for developing novel pesticides or herbicides, leveraging its specific aromatic and ketone functionalities.
• Fine Chemical Synthesis: Used in academic and industrial research laboratories for constructing complex organic molecules, natural product analogs, and specialty chemicals.
• Chiral Catalyst or Ligand Development: The defined stereocenter makes it a candidate for modification into chiral auxiliaries, ligands for asymmetric catalysis, or resolving agents.
• Material Science Research: Potential monomer or precursor for synthesizing specialized polymers or organic electronic materials due to its conjugated aromatic system.

Basic Information

Product Name	[R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-Methoxyphenyl)-1-Propanone
CAS No.	4842-48-2
Molecular Formula	C16H16O4
Molecular Weight	272.30 g/mol
Synonyms	(R)-(-)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one; (R)-2,4-Dihydroxy-4'-methoxydihydrochalcone; (R)-(-)-2,4-Dihydroxy-4'-methoxydihydrochalcone; (R)-4'-Methoxy-2,4-dihydroxydihydrochalcone; (R)-Dihydrochalcone derivative; (-)-[R]-DHC; (R)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)-1-propanone; (R)-enantiomer of 4842-48-2
EINECS	Contact for details

Quality Control

Our [R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-Methoxyphenyl)-1-Propanone is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (R-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.