Description

4-Acetylthiobutyronitrile is a versatile sulfur-containing organic intermediate with a unique nitrile and thioester functional group profile. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. Industries that require it include fine chemical manufacturers, pharmaceutical R&D labs, and agrochemical companies developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of thiol-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage its sulfur moiety.
• Fine Chemical Building Block: Serves as a versatile synthon for constructing heterocyclic compounds and other specialty chemicals.
• Ligand and Catalyst Research: Employed in the preparation of sulfur-based ligands for metal catalysis and coordination chemistry.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials.
• Bioconjugation Chemistry: The reactive nitrile and thioester groups make it useful for protein labeling and bioconjugation techniques.

Basic Information

Product Name	4-Acetylthiobutyronitrile
CAS No.	4781-82-2
Molecular Formula	C6H9NOS
Molecular Weight	143.21 g/mol
Synonyms	4-(Acetylthio)butyronitrile; 4-Acetylmercaptobutyronitrile; 4-(Acetylsulfanyl)butanenitrile; Butanenitrile, 4-(acetylthio)-; NSC 163044; Acetylthiobutyronitrile; S-Acetyl-3-mercaptopropionitrile; 3-Cyano-1-propanethiol acetate
EINECS	Contact for details

Quality Control

Our 4-Acetylthiobutyronitrile is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.