Description

Ethyl Chlorooxoacetate is a versatile and highly reactive organic ester, serving as a critical building block in advanced chemical synthesis. Its value lies in its bifunctional nature, featuring both an ester and a highly electrophilic acid chloride group, enabling efficient carbon chain extension and heterocycle formation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a high-purity intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antibiotics, antivirals, and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, contributing to novel modes of action.
• Peptide Mimetics & Protease Inhibitors: Employed to introduce keto-acid functionality, which is crucial for designing enzyme inhibitors and biomimetic compounds.
• Heterocyclic Chemistry: A vital reagent for constructing oxygen- and nitrogen-containing heterocycles like furans, pyrroles, and oxazoles.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Organic Synthesis Reagent: Acts as a versatile acylating and chloroacetylating agent in multi-step laboratory and industrial-scale syntheses.

Basic Information

Item	Details
Product Name	Ethyl Chlorooxoacetate
CAS No.	4755-77-5
Molecular Formula	C4H5ClO3
Molecular Weight	136.53 g/mol
Synonyms	Ethyl Chloroglyoxylate; Ethyl Oxalyl Chloride; Chlorooxoacetic Acid Ethyl Ester; Ethyl 2-Chloro-2-oxoacetate; Oxalic Acid Monoethyl Ester Chloride; Monoethyl Oxalyl Chloride; Ethyl Oxalyl Chloride; Ethyl Chloro(oxo)acetate
EINECS	225-292-4

Quality Control

Our Ethyl Chlorooxoacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive nature, it should be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.