Description

Benzofuran-2,3-Dione is a versatile heterocyclic organic compound, also known as phthalide, which serves as a key synthetic intermediate and building block in advanced organic chemistry. Its unique dione structure on a fused benzofuran ring makes it a valuable precursor for synthesizing a wide range of pharmaceuticals, agrochemicals, and functional materials. This high-purity compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or phthalide-based structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its reactive carbonyl groups enable the construction of complex bioactive molecules.
• Organic Synthesis & Research: Serves as a versatile starting material or reagent in academic and industrial research for developing novel heterocyclic compounds, ligands, and catalysts.
• Dye & Pigment Manufacturing: Acts as a precursor in the synthesis of organic dyes, pigments, and optical brighteners due to its conjugated system.
• Material Science: Employed in the development of advanced polymers, resins, and functional organic materials that require specific benzofuran-based monomers.
• Flavor & Fragrance Industry: Can be used as an intermediate in the synthesis of certain aroma chemicals and fragrance compounds.

Basic Information

Product Name	Benzofuran-2,3-Dione
CAS No.	4732-72-3
Molecular Formula	C8H4O3
Molecular Weight	148.12 g/mol
Synonyms	2,3-Benzofurandione; Phthalide; 1(3H)-Isobenzofuranone; 3-Hydroxyphthalide; 3-Hydroxy-1(3H)-isobenzofuranone; 2-Carboxybenzaldehyde cyclic form; 1,3-Dihydro-3-hydroxy-1-isobenzofuranone; NSC 402124
EINECS	225-231-2

Quality Control

Our Benzofuran-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.