Description

17-Epi-Ethynyl Estradiol is a synthetic steroidal estrogen derivative, structurally related to ethynyl estradiol. This compound is of significant interest in pharmaceutical research and development, particularly for its potential biological activity and as a key intermediate or reference standard. It serves the needs of research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, hormone research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor binding, metabolism, and hormonal pathways.
• Analytical Standard: Employed in quality control laboratories for method development, calibration, and impurity profiling in steroid analysis via HPLC, GC, or LC-MS.
• Academic & R&D: Utilized in university and institutional research for exploring structure-activity relationships (SAR) of estrogenic compounds.
• Fine Chemical Synthesis: Acts as a specialized starting material for custom synthesis and the production of high-value, low-volume steroid derivatives.

Basic Information

Product Name	17-Epi-Ethynyl Estradiol
CAS No.	4717-38-8
Molecular Formula	C20H24O2
Molecular Weight	296.40 g/mol
Synonyms	19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol; 17α-Ethynylestra-1,3,5(10)-triene-3,17β-diol; 17-Epiethynylestradiol; 17α-Ethynyl-17β-estradiol; Ethynyl Estradiol EP Impurity C; EE Impurity C
EINECS	Contact for details

Quality Control

Our 17-Epi-Ethynyl Estradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity reference materials and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.